The TIMI-II 36 and GISSI-2 37 data normal lv function heart failure confirm a similar and comparably low mortality rate in patients with normal LV function (LVEF > 50%; 1.2%), as reported earlier by the MPRG (see Fig. 35-9). 10 However, if …
Heart failure always causes circulatory failure, but the converse is not necessarily the case, because various noncardiac conditions (eg, hypovolemic shock, septic shock) can produce circulatory failure in the presence of normal, modestly impaired, or even supranormal cardiac function.
Angiotensin-converting enzyme (ACE) inhibitors have been shown to reduce mortality and myocardial infarction (MI) in patients with heart failure due to reduced left ventricular (LV) systolic function. Three recent trials have evaluated ACE inhibitors in patients with vascular disease, but normal LV systolic function…
This editorial refers to ‘Routinely reported ejection fraction and mortality in clinical practice: where does the nadir of risk lie?’ †, by G.J. Wehner et al., on page 1249. For decades, heart failure has always been divided into those with normal vs. reduced left ventricular (LV…
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